An experiment was conducted at Breeder Seed Production Centre, Bangladesh Agricultural Research Institute(BARI), Debiganj, Panchagarh during 2010-11 to test the potentiality of five clonal potato hybrids with two check outstanding varieties Diamant and Cardinal. The clones were 4.5 W, 4.15, 4.26 R, 4.27 and 4.40. The experiment was laid out in randomized complete block design with three replications. The unit plot size was 3m x3m, maintaining 60cm x25cm spacing between two rows and from tuber to tuber. Well sprouted whole tubers of all varieties and lines were used as planting material. The doses of manures and fertilizers viz. Cow dung 10 t/ha, Urea 350 kg/ha, Triple super phosphate (TSP)250 kg/ha, MP 275 kg/ha, Gypsum 120 kg/ha, Magnesium sulphate, Zinc sulphate 10 kg/ha and boric acid 5 kg/ha were applied in the field. Cow dung, half of the dose of Urea, TSP, Murate of potash (MOP), Gypsum, Magnesium sulphate, Zinc sulphate and Boric acid were used as basal. The remaining half of the dose of Urea was applied during earthing up. Seed tubers were planted on 22 November 2010. Weeding was done by manually as and when necessary to keep the plots free from weeds. For easy aeration and to conservation of soil moisture, the soil was mulched by breaking the crust. First irrigation was done after 30 days after planting and subsequently 3 irrigations were done at 20 days interval after first application. Two times earthing up were done during the crop growing period. The first earthing up was done at 30 DAP along with urea and second one after 45 DAP. Percent emergence was measured by recording the emergence of tubers at 30 DAP out of 60 tubers planted and converting it to percentage. The height of the plant sample was measured in centimeter from the ground level to the tip of the longest shoot. Percent foliage coverage was recorded by eye observation at 60 days after planting. Plant vigor was also measured by eye estimation. It was scored up to 8. Higher the vigor higher was the score. Number of stem/hill was recorded at 60 days after planting. Number of tuber/hill, tuber weight/hill was taken during final harvest. Yield data were recorded two times, one at 65 and another at 90 days after planting. Yield data was taken from the whole plot. The severity of devastating disease called late blight caused by Phytophthora infestans was recorded when it showed up in the plot after planting following 1-9 rating scale according to Henfling (1979) by selecting 10 plants randomly from each unit plot. To control late blight of potato contact and systemic fungicide were used at 7 days interval until harvest the crop. Percentages of disease reaction on stem canker, potato leaf roll virus, potato mosaic virus were also observed at 60 days after planting. The data obtained for yield contributing character and yield were statistically analyzed to find out the significance of differences among the treatments. The mean values of all the characters were evaluated and analysis of variance was performed by MSTAT software package (Gomez and Gomez, 1984). The significance of the differences among pairs of treatment means was calculated by Duncan multiple range test (DMRT).